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199 – Nattokinase and Cardiovascular Health – My Interview with Dr. Ralph Holsworth

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Nattokinase is a particularly potent treatment because it enhances the body’s natural ability to fight blood clots in several different ways and has many benefits including convenience of oral administration, confirmed efficacy, prolonged effects, cost effectiveness, and can be used preventatively. Nattokinase is a particularly potent treatment because it enhances the body’s natural ability to fight blood clots in several different ways and has many benefits including convenience of oral administration, confirmed efficacy, prolonged effects, cost effectiveness, and can be used preventatively. It is a naturally occurring, food dietary supplement that has demonstrated stability in the gastrointestinal tract. The properties of nattokinase closely resemble those properties of plasmin so it dissolves fibrin directly! More importantly, it also enhances the body’s production of both plasmin and other clot dissolving agents, including urokinase. Nattokinase may actually be superior to conventional clot-dissolving drugs such as urokinase, and streptokinase, which are only effective therapeutically when taken intravenously within 12 hours of a stroke or heart attack. Nattokinase, however, may help prevent the conditions leading to blood clots with an oral daily dose of as little as 2,000 fibrin units (FU). NattokinaseIn this interview, Dr. Holsworth will discuss the origins of nattokinase and the emerging science that reveals the benefits. The basic issue here is that fibrin is the factor in our blood that forms blood clots. Too much fibrin thickens the blood increasing one's risk of cardiovascular disease. Consumption of nattokinase has been shown to enhance fibrinolytic activity leading to reduced fibrin in the blood. Nattokinase has also shown benefits for blood pressure support. Here is a quote from Dr. Holsworth's paper: "Natto, made from fermented soybeans, is a traditional Japanese food. Many people enjoy it for its distinctive flavor, enlivened by the activity of Bacillus subitilis. Natto has a long history, and some have theorized that it may even have a prehistoric origin, possibly circa B. C. It has at least been ascertained that natto has been popular since the Edo period, 400 years ago. Originally, natto was utilized as a folk remedy for heart and vascular diseases, fatigue, and beriberi. In 1980, Dr. Hiroyuki Sumi et al. found that natto contains a potent fibrinolytic enzyme, which they named nattokinase. blood_clotIt was confirmed that oral administration of nattokinase (or natto) produced a mild and frequent enhancement of the fibrinolytic activity in the plasma, as indicated by the fibrinolytic parameters, and the production of tissue plasminogen activator. Nattokinase capsules were also administered orally to dogs with experimentally induced thrombosis, and lysis of the thrombi was observed by angiography. It was shown that the oral administration of natto and nattokinase enhance the fibrinolytic activity in plasma. Conclusion Nattokinase may prove to be a defibrinogenating enzyme that drastically decreases blood viscosity. Decreasing blood viscosity strikes at the root of arteriosclerosis and atherosclerosis as well as hypertension, peripheral vascular disease and congestive heart failure.

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